NCI R37 (CA-30488) - Goff
This project consists of a genetic analysis of the replication cycle of the Moloney murine leukemia virus. We are generating mutations in a cloned copy of the proviral DNA, and determining the consequences of the mutations on viral replication after introduction of the DNA into mouse cells in culture.
PI, 2/01/99 to 1/31/14
Howard Hughes Medical Institute - Goff
Support is provided to identify and characterize host genes interacting with the gene products of retroviruses and host oncogenes.
PI, 5/01/93 to 8/31/14
NYSTEM N082G-152 contract C024329 - Goff
Characterization of the retroviral silencing machinery in embryonic stem cells
(Investigator Initiated Research Project)
PI, 1/01/2009 to 12/31/2012